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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12aafac38358e07f12aa3fdff46ce2d161aa70f53ed154a87d04cef5f2c23292' 
  AND token = 'Vn6qDx7+a7kKLt96zQ8aX4NNGgPc8tU/tMO3zY4eQk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}