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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cb21d0e39d79597d4a1b6e2a4cff033bc7477a03aaf8d66445cf3c277078b2a' 
  AND token = 'sQG0OisBeA6NG1uGu8kDF6kKtFflaO2NekwltXZ6b/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}