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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cad64b643d905074122aef3d2fe2452085b5f3e3230ab70e8633fdc19bcf6d7d' 
  AND token = 'WU8/8pxMa7QrV2YteZ89JZ17YazTrUMQa2EwzyQIMQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}