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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52782d4232c66b647211239fc7eeeb449783ee62e0c1c68e84687332fd37d2ff' 
  AND token = 'Gyg6lATb1sBwUWpMK0+xzJ3E4ROqxm8JbHhqQw83eL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}