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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6c3112911e6b1821b9e366917fe9c94dd291322aa8d1817594b97c00c2a0d0f' 
  AND token = 'ONM/4NDeVqeW8jzuI5qof9dtTbY92wrcR7bqd3Hv+9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}