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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72274cb39357a62ff17aefc87a24a12f5f837eebce9b875b72c2417bfab2bdb0' 
  AND token = 'G7ZTFUqWDl7A4KfNU3JmoD2ExT3LFxSjy/6ocROe5tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}