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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e9e33eed2e90ffc4722671f657fac72b45589bd10143008a8497e4d3bc8d53a' 
  AND token = 'yS8D9brEgmCIgB7yyFEiuRbXUHhBJgPffBGsC8w4BLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}