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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd25c37859bad382943a15a8c3cc7e5b79623b29a2828a85456ef5be94cf50b71' 
  AND token = 'mX5IpYEqGLHyMvY7BoJdUla8J981Z3dMEdUosQCymMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}