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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb006a3291e73b7a5b313fd9214539554f4bf415d3d62a6ab02d917322e2d0eb' 
  AND token = 'sAeevAJc2B/PA9cTcH9u3rvfR2W7tyAOxiNiDHi5Q78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}