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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4898a700bfc25a28bcdc26b3d08cda073c8d7983ae8917518af8479e287d7729' 
  AND token = 'lctwATQ7VI5EZV/3VXc1mNantiZKNk9xhTk+GAcCkak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}