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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '368d2205c3f0c95525e0335c23fd16f0597f4a85b1b7cc8c34631d1a46474248' 
  AND token = 'tqxnLCze2133MfJqKC3FONHjHtj5mSddiBL0oWwxz7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}