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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fd50e00156aaf491c25dc1b6b9b85d1c8ed023073e851874d3b51ed0ad74054' 
  AND token = 'LlDVedFqP9C9TvbNIYQahcr+OSlMOOx5xpI7efyHMW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}