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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '784d6487ba093ab220b728f34fc4addd5a2f2f718807bad207a9292e88a3fb7d' 
  AND token = 'Pt+ilMLy7xUTI+Zksx0ECkiAw/okB8fB3fbseKl/S3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}