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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eac596467095ddec238a15208017ad5e1ee94c0add50556559b9f665370661d2' 
  AND token = '8Cm12dDMmVEe4LtFlF0eAY00UvMACKcGP2mOIml64sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}