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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8286984931ec9290d8f0bf8c323ff2f2357abb0f0d21780e222f425a6de10bc' 
  AND token = 'MRMV2igIcduuezDm1R8YfurzbRCsrZF3mjHEt863cQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}