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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e397bc4ff4dcc7f28438a2fc5cf678baebb1c9e0fae94206d994fef276c6c56b' 
  AND token = '8sOQ5vfGBXlagt6bQkN8n90oGdweK8zSFljeacNM3GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}