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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06aa5a35fc4ea690d20c0bb4469c1e2c797cdf6f89caf57d7a1a02c0f49fd706' 
  AND token = 'uEco9HaLy0kZQL6PGArGj1CjVSNhmUGP4qTnE5R8kCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}