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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eba185c855aa15abc6f092294ff5fc93e30d1baa6fc4af6931202c630b59250' 
  AND token = 'e34Vlp4GUEtRmyyNMqM/PLreazj0mHBxCTnZP3LNCBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}