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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b66570e16356cda2ccbf302e2cfac190c0588b7d376e01e852715e89d7dbdaae' 
  AND token = 'NAPQruqnmZFGzZUotd39GZZGnhF9oaqZ0y/oiI/MnYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}