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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd009c62c56c65ed1736e2ea32ea8ce15eb966120294e06b2545a3e637260def' 
  AND token = 'uvf01T8bvgOjcHRS1rEgrPLoWCz4t7z3z6XEZYHeTIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}