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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39b168d3c567510903fe1d6101a4a143b2fcc2f804d09137ead65b775040aa6a' 
  AND token = 'Y7QO4Pltw45WPGINx9FqWzrgFmOhmc7auNj4T4DXaEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}