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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '411e787d7c604cc31efd6233b68a5f6023a809aed28929601c3e1a2fcd0bbdad' 
  AND token = '9dJF2HlDx+u0hdbMBu5ezmb7ttb0Db9LBlGfBK2NAHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}