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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e1436ae53dd524aecbd9c0e1d2072f81983d1616d77539e18b7fc79052fd94f' 
  AND token = '5PXTlhEskJCG7e3xoUjRCvf1jf32ugNlG5ZpL/sJRH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}