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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f4de679b36ed831653e96c4aaf0cc1b00a57eff920e1fb9fc9faf0d8d082b53' 
  AND token = 'Iw5mc0NIHuV5rHfwDUHHGMT89cfFFB3IO8CpXWINCuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}