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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6100e9884eb1cc956ce4109fab9512f37d1107da146feb853f28cba0032924' 
  AND token = 'XOhFgsJoS2guMsKjZ1Ek2KEk+eHreHTrndbg6vFSXqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}