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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27ab0958fe95ef897aa0159825697b5d4cb9c624a8d5439a3f7b3af229263ed6' 
  AND token = 'E91sz2gITnFydmcrZxfvaODlkI5ltrLJytqb8iAy2Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}