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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4386ec7021e0d9c99257dc97e1686e09cf49e652acb4b3d513672e0e9a8fa438' 
  AND token = 'VPNnbI46614pRNlrX177SmhXefbq1Ra/2FiXM1yxTB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}