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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e87d4bc7899cabf6023db70a7fb5eda9edc95d13cc29176e54b7de6502d80d' 
  AND token = 'AgO0wGY7gC4XYU/VQ9eLp0qh7MdRsIkdDljzUqEZmL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}