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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888eb08a8922f5c29561ff1485f6609e22fe2af4345a234711faaf4594e567e2' 
  AND token = 'ZfdcNP7WXPyR4J4JepXPToJZvYNtFO7p3RPoxSI7SYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}