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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c87379e669dac13c147e98b0ddcaf4514705bfca0e34445e4cc84b7bd86edf8' 
  AND token = 'Lj1/oDxGwrU9N/Hk4fsrHuG1CuY+8QwASDI47Uw7fSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}