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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45aea7a4d2755d2755938adea6e9d5d1ab8156006a8a7026e4dc9b5336d3f344' 
  AND token = 'LmbanbMSbn2VUGVKwXuyExezQMREHyZabjYksWIUb8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}