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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fe11fe1950fd6c1f612c8466656f43d44359bdf68b1253a91506e7b19d62dc5' 
  AND token = 'DG3nXrV7PHQJGCa29hTDduOdFsp/5JC1P2i3GrYHRMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}