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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28dd434b3343b6ce08cc9c302d6af868d4070ab64fa47c08ad8689f87f658a31' 
  AND token = 't2xjeRDjPsAeQeejNkSc1+7ztBubItNXVnEjS0nYCO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}