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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5abac18bcf6305fd6539f2d3915e72fc8e6e39230d445fa7b4f4f07884982b0f' 
  AND token = 'zSizCknUDf0DO7/vpWNex/a0hbhCQuWph5UER0lE+rE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}