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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc6554eee7214e042acce8ed8f441793f84787b6b2114ca6210247bbf30a36f8' 
  AND token = 'xEnq1VNxuBS2boVTWJtSRjGpB8nHjx8oktYLwbbi/gQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}