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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0b2bbae167177444f3b071e4bb9e3ec0d698b6921024c9336dd688bc68c0719' 
  AND token = 'P/DLDbgUOgLY+vF7hiuw0KCKZPdAbSKTRrUSbCbTdyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}