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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cd51da2144cd4a7a385b8043391f4d9c473e3d9c29cde06fffb28c99c5dfcc6' 
  AND token = 'uXNry57sO+0A4Dfnjsys/R98BJ9k2XZQ4sKnJy7ZEgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}