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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68e2aa132343fee47249d2d8509e275486ee76054e9ab54bed31949143419b8b' 
  AND token = '53Hdm6jOwGFqsL3YiE/GRcWOBm4JosP5CFG1JodSjw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}