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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af1d419d2fbbc1a2b82f2666159585c8636eb10d50e5e83b73146ada4e9ab13e' 
  AND token = 'dVpQSTUbtyqqAJWUjQL8jAWq6LeF9TZ4htI5FbA8JAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}