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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b301a8a1744d34fe8f77dc2da0cf655306f69c8e391f0cdea007978d50adc8' 
  AND token = 'Yg32OP+K7j7He4tNcKn/k/nNHCgrT0rZTe+MtXhMpLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}