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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ef0dbe64e00f3f9cf647e0046a06e2a8004d0bf2e5d68a9c0e04155949702ab' 
  AND token = 's2x7dop2SD5fjsnTFTtlmHZXmcg4KqvSl8UScTUh3G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}