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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d9775c9e4a83d7fb948fea11327884375dd284d2958c138fb15955fded2e005' 
  AND token = 'C3UHLcBoIEEZW2sMsloOdvA/s9UR1/f4RY/HPdq/Lq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}