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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e10bb22596693d0d9368a35f586f450ed628408e3feeca7ed5c75557953a5dbc' 
  AND token = 'yJpxEqXnlkUdO1t++Ev/UEN6R+F5BHQJQiDvCkfWMrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}