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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f038ab29eaf41cbd7df7ff9cdd63f74cff5ada4890a524c1ee700ace6d7d21f' 
  AND token = 'l2ihjvMEzTtvd1g/XUobR2YTvXNaLPr7DjGR/QRX67Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}