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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37faaf054a0eb7b4de57f00f16b592bc1a4f393bbdcb9dcc5cd55465cc0f7f25' 
  AND token = 'jZKydQcCBN+HUsSPjaVB1GoQIQHZugcPAtJPZyASqFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}