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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e19ab3e2c2b27b779aa515f23061bcaf6ff7407ede010738a2f9972bc53ef21' 
  AND token = 'RahORvreXVGb40FI9S7CKPN9uQcF7lUptbOAMDmWPms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}