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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af47be7e398597be49707008a3ce178a942449d16c0037e16937f66b71885a16' 
  AND token = 'GNbvmqL5NFDa2zmXMJRXORy5bZEHpMdSfP4X1aduUl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}