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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0ce327c0928012729c73fafec91ef1b2fe6153500598b0cb004f7e58e958121' 
  AND token = 'UP9zdyxWzW9F8yNgS/TNB+mnL+l2iMxsxrpsfW0CFq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}