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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52cb5950bc9e3dcb564eb2a38811d5e0d7719fc556e95749d912540c37d43e4a' 
  AND token = 'yfcAeaCHM4Ao0ko+znOCY33GA5of2JnvpxO+pWZ6XoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}