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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8609f646a298ec0f36964bc462785887b5808c483ccd532f608326b69c58dcdf' 
  AND token = '1o67w2m/xVmYHMqCEcAfBt9GK8sAS/LLl4ak/3me4Q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}